SAM D21 Arm® Cortex®-M0+ Microcontrollers

Microchip Technology SAM D21 Arm® Cortex®-M0+ Microcontrollers (MCUs) are low-power MCUs that range from 32- to 64-pins with up to 256KB Flash and 32KB of SRAM. The Microchip Technology SAM D21 MCUs have a maximum 48MHz frequency and reach 2.46 CoreMark/MHz. The devices are designed for simple and intuitive migration with identical peripheral modules. Features include hex-compatible code, identical linear address map, and pin-compatible migration paths between all devices in the product series. All devices include intelligent and flexible peripherals, an Event System for inter-peripheral signaling, and support for capacitive touch buttons, slider, and wheel user interfaces.

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Description Datasheet Availability Pricing (USD) Filter the results in the table by unit price based on your quantity.
Qty. RoHS ECAD Model Series
Mounting Style
Package/Case
Core
Program Memory Size
Data Bus Width
ADC Resolution
Maximum Clock Frequency
Number of I/Os
Data RAM Size
Supply Voltage - Min
Supply Voltage - Max
Minimum Operating Temperature
Maximum Operating Temperature
Qualification
Packaging
Microchip Technology ARM Microcontrollers - MCU 64TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
2,956In Stock
Cut Tape
$2.67
$2.54
Reel
$2.17
MouseReel Available
Min.: 1
Mult.: 1
: 1,500
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 52 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,125C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
4,402In Stock
Cut Tape
$2.54
$2.47
Reel
$2.09
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 64TQFP,125C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
472In Stock
$3.21
$2.92
$2.65
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU 64QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
2,732In Stock
Cut Tape
$4.83
$4.64
Reel
$3.97
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 48TQFP,125C TEMP, GREEN, 3.3V, 48MHZ,T&R
Datasheet
2,138In Stock
Cut Tape
$2.72
$2.62
Reel
$2.24
MouseReel Available
Min.: 1
Mult.: 1
: 2,500
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 38 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel

Microchip Technology ARM Microcontrollers - MCU 64QFN,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
420In Stock
$2.87
$2.61
$2.37
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
313In Stock
$2.52
$2.29
$2.08
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 52 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 48TQFP,125C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
493In Stock
$2.63
$2.40
$2.16
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 38 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 64kFlash,Tray,USB,Extended Temp
Datasheet
727In Stock
$2.33
$2.14
$1.94
Min.: 1
Mult.: 1
SMD/SMT TQFP-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 128kFlash,Trays,USB,Extended Temp
Datasheet
674In Stock
$2.73
$2.51
$2.27
Min.: 1
Mult.: 1
SMD/SMT TQFP-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C Tray
Microchip Technology ARM Microcontrollers - MCU CM0,QFN64, 64kFlash,Tray,USB,Extended Temp
Datasheet
520In Stock
$3.20
$2.93
$2.66
Min.: 1
Mult.: 1
SMD/SMT VQFN-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
4,950In Stock
$4.35
$3.97
$3.58
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48TQFP GRN1.6-3.6V48MHz
Datasheet
4,414In Stock
Cut Tape
$4.26
$4.11
Reel
$3.51
MouseReel Available
Min.: 1
Mult.: 1
: 2,500
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 48QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
5,001In Stock
8,000Expected 2026/10/20
Cut Tape
$4.57
$4.43
Reel
$3.77
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48QFN GRN1.6-3.6V48MHz
Datasheet
14,753In Stock
Cut Tape
$4.16
$4.04
Reel
$3.43
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,125C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
7,109In Stock
Cut Tape
$2.93
$2.84
Reel
$2.42
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
6,087In Stock
Cut Tape
$4.42
$4.27
Reel
$3.65
MouseReel Available
Min.: 1
Mult.: 1
: 2,000
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU Low-Power, 32-bit Cortex-M0+ MCU with Advanced Analog and PWM
Datasheet
14,483In Stock
Cut Tape
$3.97
$3.83
Reel
$3.26
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT VQFN-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32TQFP,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
1,511In Stock
$2.40
$2.17
$1.97
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
2,479In Stock
Cut Tape
$2.37
$2.30
Reel
$1.95
MouseReel Available
Min.: 1
Mult.: 1
: 2,000
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
1,967In Stock
Cut Tape
$2.33
$2.26
Reel
$1.92
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
2,736In Stock
Cut Tape
$2.72
$2.64
Reel
$2.24
MouseReel Available
Min.: 1
Mult.: 1
: 2,000
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz,T&R
Datasheet
5,386In Stock
Cut Tape
$2.93
$2.84
Reel
$2.42
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel

Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 128kFlash,Trays,USB, I Temp
Datasheet
1,886In Stock
$2.80
$2.55
$2.35
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN IND TEMP, GREEN,1.6-3.6V,48MHz
Datasheet
2,711In Stock
Cut Tape
$3.14
$3.02
Reel
$2.58
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT VQFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape